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Maghnus O'Seaghdha Selected Research

NAD+ Nucleosidase (NAD(P) Nucleosidase)

12/2017Binding of NAD+-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus.
1/2017Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD+-Glycohydrolase: Evidence for Extracellular Activity.
3/2016NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus.
1/2013Streptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing.

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Maghnus O'Seaghdha Research Topics

Disease

4Infections
01/2018 - 03/2016
1Pain (Aches)
01/2018
1Necrotizing Fasciitis
01/2018
1Pharyngitis (Sore Throat)
01/2013
1Bone Resorption
04/2011
1Osteomyelitis
04/2011
1Staphylococcal Pneumonia
07/2009
1Inflammation (Inflammations)
07/2006

Drug/Important Bio-Agent (IBA)

4NAD+ Nucleosidase (NAD(P) Nucleosidase)IBA
12/2017 - 01/2013
3Staphylococcal Protein A (Protein A)IBA
04/2011 - 07/2006
1streptolysin SIBA
01/2018
1Type A Botulinum Toxins (Botox)FDA Link
01/2018
1InflammasomesIBA
01/2017
1InterleukinsIBA
01/2017
1anthrax toxin (anthrax lethal factor)IBA
03/2016
1Proteins (Proteins, Gene)FDA Link
04/2011
1Virulence Factors (Pathogenicity Factors)IBA
07/2009
1Type I Tumor Necrosis Factor ReceptorsIBA
07/2006
1Immunoglobulin G (IgG)IBA
07/2006